COSTBI 2011 - COSTBI 2011 : Current Opinion in Structural Biology & DNA Repair - A Current Opinion in Structural Biology conference

Current Opinion in Structural Biology & DNA Repair
A Current Opinion in Structural Biology conference
October 16-18, 2011, Amsterdam, The Netherlands
This meeting considers the structural biology of the major pathways of DNA repair and their interface with all DNA transactions in cell biology. Topics will stress the involvement of DNA repair complexes in decisions points in cell biology including replication, recombination, and transcription processes. Talks will include the nature of the DNA damage, our understanding of repair detection, signally, and processing mechanisms, and the connections of DNA repair responses and human health.

The structural biology of DNA repair assemblies with their conformations and interactions provides the foundation for a unified understanding of the biochemistry, genetics, and cell biology. Indeed, the structural biology of DNA repair has profound implications for the interpretation of the genetic code, the consequences of DNA mutations in human disease, and the preservation of the species.

Overall, this conference provides a critical opportunity to bring together experts in diverse fields relating to basic mechanisms of DNA repair revealed by the structural biology of the complexes. The outcomes of integrated discussions will be fundamental insights into the challenges and opportunities of DNA repair structures for linking proteins to their biologically relevant states and assemblies.

The focus of the conference will be on the following themes:

Chromatin Remodeling and DNA repair
Replication, mismatch repair and genome fidelity
Nonhomologous end-joining
Compelling structural and mechanistic questions
Making Double strand break repair complexes speak
DNA Damage signaling and processing
Complex Lesions and Damage response Complexes
DNA repair and disease
Call for abstracts

Abstract submission deadline: 29th of April, 2011

The conference will take place at the beautiful NH Grand Hotel Krasnapolsky, right in the center of Amsterdam on Dam Square.

Structural Biology & DNA Repair is the third in a new and exciting series of conferences sponsored by the timely and popular Current Opinion journals. These conferences provide a new level of direct interaction between the leaders in the scientific field and the attending delegates. Emphasis will be placed on latest unpublished results, extended discussion periods and direct interactions with leaders in the field. No more sitting through long talks with very little time for discussion; each conference is designed to facilitate extended discussion periods with dedicated networking sessions.

Invited Speakers

Prof. Lorena Beese, Duke University, USA
Prof. Walter Chazin, Vanderbilt University, USA
Prof. Aidan Doherty, University of Sussex, UK
Dr. Jessica Downs, University of Sussex, UK
Prof. Tom Ellenberger, BiophysicsWashington University, USA
Prof. Mark Glover, University of Alberta, Canada
Prof. Karl-Peter Hopfner, Ludwig-Maximilians-University Munich, Germany
Asso. Prof. Murray Junop, McMaster University, Canada
Prof. Caroline Kisker, University of Würzburg - Rudolf Virchow Center, Germany
Dr. Oscar Llorca, Spanish National Research Council, Spain
Prof. Laurence Pearl, University of Sussex, UK
Dr. Lars C. Pedersen, NIH, USA
Dr. Luca Pellegrini, University of Cambridge, UK
Dr. Stephen Smerdon, MRC National Institute for Medical, UK
Dr. Dale Wigley, The Institute of Cancer Research, UK
Dr. Claire Wyman, The Erasmus Medical Center, The Netherlands
Dr. Wei Yang, NIH, USA