2024 - Double Dippers: The Secret Lives of Serial Study Subjects

Clinical trials rely on valid results from study participants to ultimately advance a product to market but an estimated 8 percent of participants enrolled in a trial could potentially be enrolled in multiple studies at different research sites.
Recognizing that these “professional patients” or “duplicate subjects” may present safety risks to themselves, skew results and impact study outcomes, drug development sponsors need to understand how to prevent professional patient enrollment and perform appropriate pre-screening as part of their comprehensive recruitment strategy.
In this webinar, the speakers will first discuss the many reasons that participants may attempt to enroll in multiple studies — whether they are motivated financially or seeking access to standard healthcare or a novel treatment — and the typical methods used for enrolling in a study.
Citing recent statistics, they will also share the types of large-scale studies that have been impacted by this ongoing issue, which can be compounded when multiple sites are in the same city. The perspectives of sites will also be discussed to provide insights into the standard due diligence required at the site level to weed out professional patients.
For example, sites continually face the challenge of relying on participant-supplied information, such as health conditions, current symptoms, current use of prescribed medication and/or recreational drugs and even valid identification. As the enrollment of professional patients in a trial can lead to biased or unreliable data, attendees will learn about their overall impact to study integrity and the burden sponsors often face in identifying and rectifying problematic data.
The webinar will conclude with a discussion of several measures that can help prevent multiple enrollments and enhance patient safety as part of a structured Quality by Design initiative. The experts will also share proactive operational strategies from site selection techniques to protocol design. Finally, attendees will learn how detection technologies can help identify duplicate participants, confirm eligibility and ensure the selection of high-quality subjects.
Register for this webinar today to delve into the reasons behind multiple patient enrollments and the challenges faced by sites during participant screening and impact on large-scale clinical trials.
Keywords: Clinical Research, CRO, Patient Recruitment, Therapeutic Areas, Patient Enrollment, Clinical Sites, Study Sites, Participant Diversity, Participant Engagement, Clinical Trial Enrollment, Sites, Quality