2025 - Principles for Sustainable Flash Chromatography: Reducing, Reusing and Optimizing for a Greener Workflow

Discover in this webinar how technology can be leveraged to advance green initiatives, specifically when it comes to purification, the most wasteful component of the small molecule synthesis workflow.
Greener practices in chemistry labs like reducing waste generation and increasing use of safer solvents are major focus for organizations and research groups that synthesize and purify new molecules or drug candidates. Automated flash purification offers a fast, flexible and cost-effective method for purifying synthetic products, allowing researchers to focus on more important tasks.
However, built-in purification gradients have encouraged researchers to minimize optimization of their chromatographic methods. It is well established that purification adds a significant amount of solvent usage due to unoptimized methods, requiring duplicated efforts when the first purification fails.
Additionally, several solvents that have been a common place in chromatography are now classified as harmful and hazardous, leading to use restrictions and the need to develop improved methodologies for benchtop chromatography while not sacrificing the speed of delivery of novel molecules.
During this webinar, the expert speakers will present strategies for flash purification as it is commonly performed but highlight imbedded, improved technology that allows for simple optimization of gradients that reduce solvent usage. They will also highlight alternative chromatographic strategies that reduce or eliminate restricted solvents for greener purifications overall.
Register for this webinar to explore how automation and optimization in flash purification can considerably reduce waste and hazardous solvent use in small molecule synthesis.
Keywords: Drug Development, Chromatography, Analytical Testing, Commercial Manufacturing, Liquid Chromatography, Bioanalytical Testing, Cation Exchange Chromatography, Quality