2024 - Revolutionizing Biomarker Development: Automated Detection and Isolation of Extracellular Vesicles

In this webinar, the expert speakers will discuss a one-step automated method for affinity-specific detection, quantification and isolation of extracellular vesicles for downstream analysis, which would lead to unbiased and reproducible development of extracellular vesicle-based biomarkers in disease and therapy research.
Specific detection, quantification and isolation of extracellular vesicles is a particularly challenging task due to the heterogeneity of extracellular vesicles and the complexity of matrices in which they are typically found such as culture medium or blood plasma. The analytics for extracellular vesicles combined with liquid biopsy could lead to earlier diagnosis and stratified treatment that will save lives (e.g. cancer mortality reduction by 20-25 percent) and lower the healthcare burden cost (>5 percent reduction).
However, current methods to purify and quantify extracellular vesicles take a long time, introduce a bias and are costly and imprecise, thereby hampering progress in the research and development related to extracellular vesicles. However, the lack of methods to characterize the whole extracellular vesicle directly in crude samples restricts clinical sensitivity in diagnostics.
The expert speakers will be discussing a breakthrough label-free fiber-optic method in an automated platform for biomolecular sensing. This method combines affinity-based quantification with simultaneous affinity isolation or downstream analysis.
This integrated solution using a sensor dip-in probe is a new, selective, automated (scalable), fast (hours) and specific (purity up to 95%) method to accurately quantify and isolate extracellular vesicles directly from cell culture supernatant and plasma samples. Proof of concept data will be presented to demonstrate yield for downstream analysis and for specific capture of circulating neuronal tissue extracellular vesicles from human plasma.
Register for this webinar to learn how research studies and analysis workflows can become more efficient and effective from one-step immunospecific analytical isolation and collection of biologics, exosomes and extracellular vesicles or even of cells in suspension.
Keywords: Pharmaceutical, Biotech, Biomarkers, Clinical Laboratory, Diagnostics, Laboratory Testing, Laboratory Technology, Extracellular Vesicles, Laboratory Management, CDMO/CMO