2024 - Optimizing Amorphous Solid Dispersions: Overcoming Scale-Up Challenges with Next-Generation Technologies

As the number of poorly soluble molecules entering the pipeline has increased, the application of amorphous solid dispersions development has grown. With the advent of next-generation ASD technologies, like KinetiSol™ Technology, drug developers are setting new standards in scalability, sustainability and performance.
Common manufacturing methods for amorphous solid dispersions (e.g., spray drying and hot melt extrusion) can present scale-up challenges such as feed rate and particle size variability between scales; flow and compatibility of the resulting amorphous solid dispersion; environmental impact of raw materials during processing and the heterogeneity and stability of feed solution. These factors can negatively impact product performance and manufacturability.
In this webinar, the expert speakers will share their scale-up experiences and perspectives on opportunities to improve technology transfers for amorphous solid dispersions. They will define best practices for a successful scale-up and a more complete and efficient tech transfer for the commercialization of amorphous solid dispersions.
Register for this webinar today to learn how scale-up challenges faced during the development of amorphous solid dispersions can be overcome.
Keywords: Pharmaceutical, Drug Development, Pharmaceutical Manufacturing, Drug Manufacturing, Amorphous Solid Dispersions, Commercial Manufacturing, Pharma, API/Formulation Development, CDMO/CMO, Basic Research