2023 - Long-Acting Injectables (LAI): Microsphere Design, Development and Scale-up

Register for this webinar on long-acting injectables and learn about the selection and optimization of long-acting microsphere formulations with releases ranging from weeks to one year, applying a diverse portfolio of bioresorbable polymers to a unique polymer-based injectable microsphere platform.
The presentation will showcase selection and optimization of long-acting microsphere formulations with releases ranging from weeks to one year, applying Ashland’s Viatel™ polymer portfolio to Oakwood Laboratories’ Chroniject™ platform. Ashland and Oakwood Laboratories will present together, respectively discussing the chemistry of bioresorbable polymers applied to various parenteral formulations and a microsphere technology platform that offers reproducible, scalable, and consistent critical quality attributes under cGMP for multiple therapeutic indications.
Ashland will show how understanding the chemistry and versatility of Viatel™ polymers helps solve challenges in controlled drug release formulations and medical devices. Ashland will also introduce their NEW Viatel™ Ultrapure polymer grades and detail the advantages of ultra-low (≤ 0.5%) residual monomer specifications.
Oakwood Laboratories will present two small molecule active pharmaceutical ingredient (API) microsphere case studies, (1) from formulation development through scale up and (2) highlighting common scale up challenges and solutions. They showcase how varying process parameters and polymer chemistries based on lactide and glycolide make it possible to optimize drug load, release duration, particle size, and encapsulation efficiency.