2022 - Dive Deep Into AAV Capsid Stability & Genome Ejection With Uncle

Problem
You worked hard on zeroing in on a serotype, then establishing a cell line and finally purifying only full, monodisperse AAV. Now you want to make sure that your AAV is in a formulation that keeps the capsids stable, prevents them from aggregating and has them retain their payload until you can put them to use.
Solution
Uncle is the all-in-one stability platform to help you track stability of your AAV under different conditions. Run a quick thermal ramp, test long-term stability and check out how the vector performs in freeze-thaw cycles. Uncle has all these applications covered and requires only 9 µL per sample for up to 48 samples.
Proof
Tune in to our webinar and see for yourself how Uncle is used to characterize stability of 3 serotypes in 3 formulation conditions. We’ll walk through thermal ramp and isothermal experiments, repeat freeze-thaws and ultimately show you some crucial pieces of the AAV stability puzzle.