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a: Reported in at least 2% of Linzess -treated patients and at an incidence greater than placebo b: "Abdominal pain" term includes abdominal pain, upper abdominal pain, and lower abdominal pain. The safety of a 72 mcg dose was evaluated in an additional placebo-controlled trial in which 1223 patients were randomized to Linzess 72 mcg, 145 mcg, or placebo once daily for 12 weeks (Trial 5).Our Linzess (linaclotide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects . You may report side effects to FDA at 1-800-FDA-1088.Do side effects of Linzess vary depending on the strength (72 mcg, 145 mcg, or 290 mcg)? In some cases, yes. For example, diarrhea was the most commonly reported side effect in studies of Linzess ...Linzess side effects . Get emergency medical help if you have signs of an allergic reaction to Linzess : hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Linzess and call your doctor at once if you have: severe or ongoing diarrhea; or.Note: This document contains side effect information about linaclotide. Some of the dosage forms listed on this page may not apply to the brand name Linzess . Summary. Common side effects of Linzess include: diarrhea. Other side effects include: flatulence. See below for a comprehensive list of adverse effects . For the ConsumerLinzess' effects are due to an increase in the production of a chemical called cyclic guanosine monophosphate which increases fluid secretion into the intestine and reduces the sensitivity of pain -sensing nerves. Common side effects of Linzess include. diarrhea, stomach pain, gas, stomach distention. Serious side effects of Linzess include.
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