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Ranexa ( ranolazine ) is a prescription drug with a unique mechanism of action to treat stable angina, which is chest pain caused by an inadequate blood supply to the heart muscles. Ranexa is an anti-ischemic and anti-anginal drug. It works by inhibiting what is known as the "late sodium current" to reduce sodium overload in the heart.Ranexa is a prescription medicine used to treat the symptoms of chest pain . Ranexa may be used alone or with other medications. Ranexa belongs to a class of drugs called Antianginal, Non-nitrates. It is not known if Ranexa is safe and effective in children younger than 18 years of age. What are the possible side effects of Ranexa ?Grapefruit and grapefruit juice may interact with Ranexa and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor. Ranexa side effects. Get emergency medical help if you have any signs of an allergic reaction to Ranexa : hives; difficult breathing; swelling of your face, lips, tongue, or throat.Uses for Ranexa . Ranolazine is used to treat chronic angina (chest pain). This medicine is usually used together with other medicines (eg, ACE inhibitors, angiotensin receptor blockers, calcium channel blockers, beta-blockers, nitrates, antiplatelets, or lipid-lowering medicines). This medicine is available only with your doctor's prescription.The most common adverse events that led to discontinuation more frequently on Ranexa than placebo were dizziness (1.3% versus 0.1%), nausea (1% versus 0%), asthenia, constipation, and headache (each about 0.5% versus 0%). Doses above 1000 mg twice daily are poorly tolerated.Some of the dosage forms listed on this page may not apply to the brand name Ranexa . Summary. More frequent side effects include: constipation, dizziness, and nausea. See below for a comprehensive list of adverse effects. For the Consumer. Applies to ranolazine: oral tablet extended release.The chief use of Ranexa is to treat people with chronic stable angina. Ranexa can significantly reduce the frequency of angina episodes and increase the amount of exercise that can be performed without experiencing angina. It is usually combined with standard drug therapy for angina. 1. In addition to standard therapy, a few studies have ...
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