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See full list on drugs. com Approval date: August 17, 2015. Strength (s): 12.5MG [ AB], 25MG [ AB] Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Xenazine . These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy.Xenazine Co-Pay Assistance Program: Eligible commercially insured patients may pay $10 per 30-day supply prescription; for additional information contact the program at 888-882-6013. Applies to: Xenazine . Number of uses: Per prescription until program expires. Form more information phone: 888-882-6013 or Visit website. The dose of Xenazine should be individualized. Dosing Recommendations Up to 50 mg/day The starting dose should be 12.5 mg/day given once in the morning. After 1 week, the dose should be increased to 25 mg/day given as 12.5 mg twice a day. Xenazine should be titrated up slowly at weekly intervals by 12.5 mg daily, to allow the identification of a tolerated dose that reduces chorea. If a dose of 37.5 to 50 mg/day is needed, it should be given in a three times a day regimen. The maximum recommen... May 24, 2022 · Each XENAZINE ( tetrabenazine ) Tablet contains either 12.5 or 25 mg of tetrabenazine as the active ingredient. XENAZINE ( tetrabenazine ) Tablets contain tetrabenazine as the active ingredient and the following inactive ingredients: lactose, magnesium stearate, maize starch, and talc. Individualization of Dose Uses for Xenazine Tetrabenazine is used to treat chorea (a movement disorder) that is caused by Huntington disease. Tetrabenazine works in the central nervous system (CNS) to prevent the absorption of certain chemicals (such as dopamine and serotonin). This medicine is available only with your doctor's prescription. Before using XenazineJul 06, 2022 · Approval date: August 17, 2015. Strength (s): 12.5MG [ AB], 25MG [ AB] Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Xenazine . These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. General Dosing Considerations What is Xenazine ? Xenazine reduces the amount of certain chemicals in the body that are overly active in people with Huntington's disease. Xenazine is used to treat Huntington's chorea (uncontrolled muscle movements). Xenazine may also be used for purposes not listed in this medication guide. WarningsDosage Adjustment with CYP2D6 Inhibitors Jun 28, 2022 · Generic Name: Tetrabenazine . Brand Name(s): Xenazine . Drug Availability: Prescription. Therapeutic Classification: Vesicular monoamine transporter 2 (VMAT2) inhibitor. Available Generically: Yes. Controlled Substance: No. Administration Route: Oral (by mouth) Active Ingredient: Tetrabenazine . Dosage Form(s): Tablet Strong CYP2D6 Inhibitors Medications that are strong CYP2D6 inhibitors such as quinidine or antidepressants (e.g., fluoxetine, paroxetine) significantly increase the exposure to α-HTBZ and β-HTBZ; therefore, the total dose of Xenazine should not exceed a maximum of 50 mg and the maximum single dose should not exceed 25 mg [see Warnings and Precautions (5.3), Drug Interactions (7.1), Use in Specific Populations (8.7), Clinical Pharmacology (12.3)]. Xenazine (tetrabenazine) is a medication option used to treat abnormal and extra muscle movements in people with Huntington's disease (HD). 1 Xenazine is a vesicular monoamine transporter 2 (VMAT2) inhibitor. 1 It's thought to work by preventing VMAT2 from moving monoamines (naturally occurring brain chemicals) into vesicles.Mar 31, 2006 · Brand name: Xenazine Generic name: tetrabenazine Company: Prestwick Pharmaceuticals, Inc. Treatment for: Huntington’s Chorea. Xenazine (tetrabenazine) is a selective and reversible centrally-acting dopamine depleting drug indicated for the treatment of chorea associated with Huntington's disease. Development timeline for Xenazine Nov 02, 2021 · Xenazine. Generic name: tetrabenazine [ TET-ra-BEN-a-zeen ] Drug class: VMAT2 inhibitors. Medically reviewed by Drugs.com. Last updated on Nov 2, 2021. Uses; Warnings; Before taking; Dosage; Side effects; Interactions; What is Xenazine? Xenazine reduces the amount of certain chemicals in the body that are overly active in people with Huntington's disease. The chronic daily dose of Xenazine used to treat chorea associated with Huntington’s disease (HD) is determined individually for each patient. When first prescribed, Xenazine therapy should be titrated slowly over several weeks to identify a dose of Xenazine that reduces chorea and is tolerated. Xenazine can be administered without regard to food [see Clinical Pharmacology (12.3)]. The 12.5 mg Xenazine tablets are white, cylindrical, biplanar tablets with beveled edges, non-scored, embossed on one side with "CL" and "12.5." The 25 mg Xenazine tablets are yellowish-buff, cylindrical, biplanar tablets with beveled edges, scored, embossed on one side with "CL" and "25." Contraindications Xenazine is contraindicated in patients:
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