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Clonidine may be used to treat high blood pressure and some other conditions such as attention deficit hyperactivity disorder (ADHD). Clonidine acts on specific receptors in the brain stem called alpha-adrenoreceptors to reduce heart rate and blood pressure. The mode of action of clonidine in ADHD is not known.mental depression. paleness or cold feeling in the fingertips and toes. pounding, slow heartbeat. problems in urination or increase in the amount of urine. raised red swellings on the skin, lips, tongue, or in the throat. restlessness. seeing or hearing things that are not there. shaking. shortness of breath.Clonidine hydrochloride is an imidazoline derivative and exists as a mesomeric compound. The chemical name is 2- (2,6-dichlorophenylamino)-2-imidazoline hydrochloride. The following is the structural formula: Clonidine hydrochloride is an odorless, bitter, white or almost white crystalline powder.Chemical Class: Thiazide Related Uses for clonidine and chlorthalidone Clonidine and chlorthalidone combinations are used in the treatment of high blood pressure (hypertension). High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
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