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The effective dosage of EXELON PATCH in patients with severe Alzheimer's disease is 13.3 mg/24 hours administered once per day; replace with a new patch every 24 hours. Interruption of Treatment If dosing is interrupted for 3 days or fewer, restart treatment with the same or lower strength EXELON PATCH .The most common side effects of Exelon Patch include: headache, dizziness, depression, anxiety, tiredness, muscle weakness, stomach pain, and trouble sleeping Tell the doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Exelon Patch .Exelon improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical that is important for the processes of memory, thinking, and reasoning. People with dementia usually have lower levels of this chemical. Exelon is used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease.Exelon Patch is indicated for the treatment of mild-to-moderate dementia associated with Parkinson's disease (PDD). DOSAGE AND ADMINISTRATION Recommended Dosing Initial Dose Initiate treatment with one 4.6 mg/24 hours Exelon Patch applied to the skin once daily [see Dosage and Administration (2.4)]. Dose TitrationKeep using Exelon (rivastigmine patch ) as you have been told by your doctor or other health care provider, even if you feel well. Do not use patches that are cut or do not look right. Wash your hands before and after use. Put patch on clean, dry, healthy skin on the upper or lower back. If you are not able to do this, put on upper arm or chest.*Nausea and Vomiting: In the controlled clinical trials, 47% of the patients treated with an Exelon dose in the therapeutic range of 6 mg to 12 mg per day (n = 1189) developed nausea (compared with 12% in placebo). A total of 31% of Exelon -treated patients developed at least 1 episode of vomiting (compared with 6% for placebo). The rate of vomiting was higher during the titration phase (24% ...
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