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Dosage form: tablet. 1 tablet (1.0 g) twice daily (morning and night) for adults and pediatric patients over 12 years of age. 1/2 to 1 tablet (0.5 to 1.0 g) twice daily (morning and night) for pediatric patients 6 to 12 years of age. Since the antibacterial activity of HIPREX is greater in acid urine, restriction of alkalinizing foods and ...Hiprex taken during pregnancy can interfere with laboratory tests of urine estriol (resulting in unmeasurably low values) when acid hydrolysis is used in the laboratory procedure. This interference is due to the presence in the urine of methenamine and/or formaldehyde. Enzymatic hydrolysis, in place of acid hydrolysis, will circumvent this problem.Take after meals and at bedtime. Children up to 6 years of age—Dose is based on body weight. The usual dose is 18.3 mg per kilogram (kg) (8.3 mg per pound) of body weight four times a day. Take after meals and at bedtime. Children 6 to 12 years of age—500 mg four times a day. Take after meals and at bedtime.Along with its needed effects, methenamine (the active ingredient contained in Hiprex ) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking methenamine: Less common. Skin rash.Common side effects of Hiprex may include: painful urination; nausea, vomiting; or. rash, itching. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Hiprex side effects (more detail)HIPREX taken during pregnancy can interfere with laboratory tests of urine estriol (resulting in unmeasurably low values) when acid hydrolysis is used in the laboratory procedure. This interference is due to the presence in the urine of methenamine and/or formaldehyde. Enzymatic hydrolysis, in place of acid hydrolysis, will circumvent this problem.
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