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The 7 Best Cold Sore Remedies of 2022 Lemon balm OTC antivirals Ice Aloe vera Sunscreen Stress reduction Ibuprofen or acetaminophen When to call a doctor FAQs Takeaway Cold sores appear as blisters...Since a cold sore is caused by a virus, an antiviral can be prescribed when needed. Prescription antiviral medications for cold sores include: Valacyclovir (Valtrex) Acyclovir (Zovirax) Penciclovir (Denavir) Famciclovir Acyclovir is available as both an oral and topical option. Valacyclovir and famciclovir are only available for oral use.Cold sore medications, both prescription and OTC, rely on a variety of different active ingredients to offer relief and healing, per Dr. Shainhouse. There are drying agents (Domeboro solution, calamine lotion, zinc oxide, witch hazel ), which when dabbed on the sore help dry up the blister and its fluid.Medically reviewed by Emina Ribic (MD) on December 28, 2021. Written by Linda White (MD). What's the Best OTC Cold Sore Medicine? #1 Virulite Electronic Cold Sore Treatment #2 HERP-B-GONE Cold Sore Cream #3 Abreva Cold Sore Cream #4 Orajel Cold Sore Treatment Benefits of Over-the-Counter Creams & GelsAccording to that study and another older study from 2007, the following essential oils show antiviral effects against the herpes virus: rosemary essential oil peppermint oil tea tree oil clove...The Food and Drug Administration (FDA) approved Valtrex to treat cold sores in adults and children ages 12 years and older. The recommended dosage for treating cold sores is two 2-gram (g) doses of...
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