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Common estradiol side effects may include: nausea, vomiting, diarrhea, stomach cramps; mood changes, sleep problems ( insomnia ); cold symptoms such as stuffy nose, sinus pain, sore throat; weight gain; headache, back pain, dizziness; breast pain; darkening of the skin or skin rash; thinning scalp hair; or.Proper use of Estalis. This section provides information on the proper use of a number of products that contain estradiol and norethindrone. It may not be specific to Estalis. Please read with care. It is very important that you use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use ...Each Estalis 50 /g / 250 µg / 24 h transdermal patch contains estradiol hemihydrate equivalent to 0.51 mg estradiol and 4.80 mg norethisterone acetate in a 16 cm 2 patch and releases 50 micrograms of estradiol and 250 micrograms of norethisterone acetate per 24 hours. The active substances are estradiol (as hemihydrate) and norethisterone acetate.
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