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Simbrinza generic Simbrinza contains two active drugs: brinzolamide and brimonidine tartrate. Simbrinza is available only as a brand-name medication. It's not currently available in generic form..Simbrinza Side Effects. Generic name: brimonidine / brinzolamide ophthalmic Medically reviewed by Drugs. com . Last updated on Apr 10, 2022. Consumer; Professional; Note: This document contains side effect information about brimonidine / brinzolamide ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Simbrinza .. For the ConsumerSimbrinza Ophthalmic Drops contain a combination of brimonidine and brinzolamide. Brimonidine and brinzolamide reduce the amount of fluid in the eye, which decreases pressure inside the eye. Simbrinza is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).
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