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Doxycycline is a light-yellow crystalline powder. Doxycycline hyclate is soluble in water, while doxycycline monohydrate is very slightly soluble in water. Doxycycline has a high degree of lipoid solubility and a low affinity for calcium binding. It is highly stable in normal human serum. Doxycycline will not degrade into an epianhydro form.Take doxycycline exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take doxycycline with a full glass of water. Drink plenty of liquids while you are taking this medicine.All patients with severe or life-threatening infections: 2.2 mg/kg orally every 12 hours. Patients older than 8 years with less severe infections: -Initial dose: 4.4 mg/kg orally on the first day, given in 2 divided doses. -Maintenance dose: 2.2 mg/kg orally once a day or 1.1 mg/kg orally twice a day. At least 45 kg:Doxycycline Hyclate is an antibacterial drug synthetically derived from oxytetracycline, and is available as Doxycycline Hyclate capsules for oral administration. The chemical designation for doxycyclin is 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacene-carboxamide monohydrate.Doxycycline is an antibacterial drug synthetically derived from oxytetracycline, and is available as Doxycycline Hyclate Tablets and Capsules and Doxycycline for Oral Suspension; for oral administration. The structural formula of doxycycline monohydrate is. with a molecular formula of C 22 H 24 N 2 O 8 ∙H 2 O and a molecular weight of 462.46.Doxycycline capsules 100 mg, 75 mg, and 50 mg capsules contain Doxycycline Monohydrate, USP equivalent to 100 mg, 75 mg, or 50 mg of doxycycline for oral administration. The chemical designation of the light-yellow to pale yellow powder is alpha-6-deoxy-5-oxytetracycline. Structural formula: C 22 H 24 N 2 O 8 • H 2 O M.W. = 462.45In patients with uncomplicated gonococcal infections, doxycycline 100 mg twice daily for 7 days is given orally, although it has occasionally been given in a single dose of 300 mg followed by a second similar dose 1 hour later.Doxycycline is a light-yellow crystalline powder. Doxycycline hyclate is soluble in water, while Doxycycline monohydrate is very slightly soluble in water. Doxycycline has a high degree of lipoid solubility and a low affinity for calcium binding. It is highly stable in normal human serum. Doxycycline will not degrade into an epianhydro form.
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