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Date2022-07-30 - 2022-08-13
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Cardiac Electrophysiology: The effect of MetroGel on the QTc interval has not been adequately characterized. Pharmacokinetics Topical administration of a one gram dose of MetroGel to the face of 13 patients with moderate to severe rosacea once daily for 7 days resulted in a mean ± SD C max of metronidazole of 32 ± 9 ng/mL.Drug classes: Topical anti- rosacea agents, Vaginal anti-infectives Medically reviewed by Drugs. com . Last updated on Sep 13, 2021. The recommended dose is one applicator full of METROGEL -VAGINAL (approximately 5 grams containing approximately 37.5 mg of metronidazole) intravaginally once or twice a day for 5 days.Detailed Metronidazole Topical dosage information for adults and children. Includes dosages for Acne Rosacea and Bacterial Vaginosis; plus renal, liver and dialysis adjustments. ... For the topical treatment of inflammatory lesions of rosacea ; Usual Adult Dose for Bacterial Vaginosis. 1.3% Vaginal Gel: Insert 1 applicatorful intravaginally once ...MetroGel ( for the skin) is used to treat skin lesions caused by rosacea . MetroGel may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.Dosage form: gel. Drug class: Topical anti- rosacea agents. Medically reviewed by Drugs. com . Last updated on Mar 21, 2022. For topical use only, not for oral, ophthalmic, or intravaginal use. Cleanse treated areas before the application of METROGEL . Apply and rub in a thin film of METROGEL once daily to affected area (s).The pharmacodynamics of metronidazole in association with the treatment of rosacea are unknown. Pharmacokinetics Topical administration of a one gram dose of METROGEL (metronidazole) to the face of 13 patients with moderate to severe rosacea once daily for 7 days resulted in a mean ± SD Cmax of metronidazole of 32 ± 9 ng/mL.Bioavailability studies on the topical administration of 1 gram of METROGEL ® Topical Gel (7.5 mg of metronidazole) to the face of 10 rosacea patients showed a maximum serum concentration of 66 nanograms per milliliter in one patient. This concentration is approximately 100 times less than concentrations afforded by a single 250 mg oral tablet.
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Cardiac Electrophysiology: The effect of MetroGel on the QTc interval has not been adequately characterized. Pharmacokinetics Topical administration of a one gram dose of MetroGel to the face of 13 patients with moderate to severe rosacea once daily for 7 days resulted in a mean ± SD C max of metronidazole of 32 ± 9 ng/mL.Drug classes: Topical anti- rosacea agents, Vaginal anti-infectives Medically reviewed by Drugs. com . Last updated on Sep 13, 2021. The recommended dose is one applicator full of METROGEL -VAGINAL (approximately 5 grams containing approximately 37.5 mg of metronidazole) intravaginally once or twice a day for 5 days.Detailed Metronidazole Topical dosage information for adults and children. Includes dosages for Acne Rosacea and Bacterial Vaginosis; plus renal, liver and dialysis adjustments. ... For the topical treatment of inflammatory lesions of rosacea ; Usual Adult Dose for Bacterial Vaginosis. 1.3% Vaginal Gel: Insert 1 applicatorful intravaginally once ...MetroGel ( for the skin) is used to treat skin lesions caused by rosacea . MetroGel may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.Dosage form: gel. Drug class: Topical anti- rosacea agents. Medically reviewed by Drugs. com . Last updated on Mar 21, 2022. For topical use only, not for oral, ophthalmic, or intravaginal use. Cleanse treated areas before the application of METROGEL . Apply and rub in a thin film of METROGEL once daily to affected area (s).The pharmacodynamics of metronidazole in association with the treatment of rosacea are unknown. Pharmacokinetics Topical administration of a one gram dose of METROGEL (metronidazole) to the face of 13 patients with moderate to severe rosacea once daily for 7 days resulted in a mean ± SD Cmax of metronidazole of 32 ± 9 ng/mL.Bioavailability studies on the topical administration of 1 gram of METROGEL ® Topical Gel (7.5 mg of metronidazole) to the face of 10 rosacea patients showed a maximum serum concentration of 66 nanograms per milliliter in one patient. This concentration is approximately 100 times less than concentrations afforded by a single 250 mg oral tablet.
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