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Calibrations 2020 - Issues in Calibrations and Accuracy in Method Validation

Date2020-05-26

Deadline2020-05-26

VenueOnline, USA - United States USA - United States

KeywordsCalibrations; Method Validation; Online Webinar Training

Websitehttps://www.compliance4all.com/webinar/i...502971LIVE

Topics/Call fo Papers

Overview:
This webinar will cover validation of calibrations and the strengths, weaknesses, and appropriateness of the different types of standards. Without accuracy, a result is not acceptable.
There are many issues that affect accuracy and there are many approaches to deal with them. The importance of response, matrix effects, selectivity of identification, and other issues will be covered.
Why you should Attend: Accuracy, the ability for a methodology to give results within acceptable limits when compared to known values, is a fundamental and key requirement. Calibration is the most common approach to obtain accuracy.
Accuracy requires a comparison to a validated material. The level of confidence depends on traceability, a chain connecting the samples of interest all the way to the specific metric standards. This can be a complex task which can raise doubts in an auditor. There are different situations for the use of each of standards of the various types. How to access the validity is a key.
In calibration, fundamental reliance on linearity of response make proof of linearity important. This is more involved that only obtaining a linear regression factor or correlation coefficient.
Once proven, though, calibrations can change with various factors. Monitoring calibration behavior and using that to maintain or even improve a methodology can be very useful.
Areas Covered in the Session:
How accuracy is determined
What are the various types of standards and what are their strengths and weaknesses?
The importance of traceability
Calibration curves - what are the important criteria? Linearity versus nonlinearity, slope, intercept and what they mean
Matrix effects and how to deal with them
Using calibration data to monitor performance
Who Will Benefit:
Lab Chemists
Lab Managers
Lab Technicians
Lab Analysts
Industries into Compliance Methodology (Biotech, Pharma) Companies into Environmental Compliance or EPA
Speaker Profile
John C. Fetzer has had over 30 year experience in HPLC methods development. He has authored or co-authored over 50 peer-reviewed papers onl iquid chromatography, has served on the editorial advisory boards of the Journal of Chromatography, Analytical Chemistry, and Analytical and Bioanalytical Chemistry.
Event link:
https://www.compliance4all.com/webinar/--502971LIV...
Contact Info
Netzealous LLC, DBA -Compliance4all
Email: support-AT-compliance4All.com
Phone: +1-800-447-9407
Website: https://www.compliance4all.com/

Last modified: 2020-03-11 18:42:59