2019 - Determination of Limits of Detection in Chemical Forensic and Environmental Analysis

The various accepted methods to determine limits of detection and limits of quantitation
How different limit of detection methods are appropriate to different analytical techniques
The advantage and disadvantages of each method
The difference between instrumental and method limits of detection
How to choose the best limit of detection method that is suitable for the intended purpose of the analysis
How to design, execute and document the tests to determine limits of detection
How to calculate limits of detection from these tests
How to verify that the determined limit of detection does not produce false positives or false negatives
How to determine the limit of quantitation that has an acceptable level of uncertainty
How to prepare an SOP with instructions on how to determine a method’s limit of detection and limit of quantitation