2019 - Fundamentals of Pharmacokinetics

OVERVIEW
Pharmacokinetics are fundamental throughout drug discovery and development. The assessment of the pharmacokinetic profile on new chemical entities reduces the failure during development making the process more efficient. The pharmacokinetics of each drug is different due to its physical-chemical characteristics. The course will describe all the processes determining the pharmacokinetics of a drug and their relationship. The course will not use complex mathematics to explain the concepts and assume no previous knowledge in pharmacokinetics.
LEARNING OBJECTIVES
To learn what are the key chemical and physiological factors affecting the absorption, distribution, metabolism, and excretion (ADME) of a drug
To learn the impact of absorption, distribution, metabolism, and excretion (ADME) in defining the behavior of a drug after administration
To learn how the analysis of pharmacokinetic data in conducted
To learn the meaning of elimination half-life, clearance, and volume of distribution
Defining the relevance of ADME from both the safety and efficacy standpoints
To understand the relevance of pharmacokinetics in drug discovery and development
WHY SHOULD YOU ATTEND
Professional in the pharmaceutical industry, academia, and contract research organizations need to be familiar with the fundamentals of pharmacokinetics. This will allow an optimal design of the various pre- and clinical studies as well as a better communication with other peers. Pharmacokinetics is relevant in many areas of drug discovery and development and a basic knowledge of this discipline of those involved in R&D will streamline the overall projects.
AREAS COVERED
Absorption
Distribution
Metabolism
Excretion
Elimination half-life
Clearance
Volume of distribution
WHO WILL BENEFIT?
Professionals involved in project management, clinical operation, regulatory, manufacturing, marketing, medical writers, quality assurance, graduate students in the pharmaceutical R&D sector. Pharmaceutical technology managers, pharmacovigilance managers, toxicology managers, pharmacology managers, medical affair managers, business development managers,
SPEAKER
Dr. Stefano Persiani is within the Internal & External Innovation, Director of Translational Sciences and Pharmacokinetics at Rottapharm Biotech, Italy since the year 2000. Dr. Persiani received his Ph.D. in Pharmacy from the University of Milan, in Italy and completed his Post-Doctoral fellowship in the Department of Pathology of the University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
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